Manipulating magnetic 3D spheroids in hanging drops for applications in tissue engineering and drug screening.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23606526.
- Also identified by DOI 10.1002/adhm.201200408.
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Abstract
Magnetic spheroid manipulation can be carried out in hanging drops to generate distinctly structured heterotypic microtissues through sequential addition of cells or spheroid to homotypic spheroids. These spheroids can also be incorporated in a droplet-based assay to screen for therapeutic efficacy in prolonged studies. This simple and versatile technique can offer potential benefits in tissue engineering and drug screening applications.
Medical subject headings
- Drug Evaluation, Preclinical
- Magnetic Phenomena
- Spheroids, Cellular
- Tissue Engineering