Sorting sloppy Sonic.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23622235.
- Also identified by DOI 10.1016/j.cell.2013.04.021 and PMC identifier 4061736.
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Abstract
In the classic picture of morphogen-mediated patterning, cells acquire the correct spatial arrangement of specified fates by reading a precisely distributed gradient of morphogen. Xiong et al. now provide evidence for an alternate strategy-cells of the zebrafish neural tube actively sort to their correct positions following disordered specification by Sonic hedgehog.