Similarities between familial and sporadic autopsy-proven progressive supranuclear palsy.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 23635960.
- Also identified by DOI 10.1212/WNL.0b013e318294b2eb and PMC identifier 3716405.
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Abstract
Progressive supranuclear palsy (PSP) is a relatively common neurodegenerative tauopathy clinically characterized by parkinsonism, axial rigidity, and supranuclear gaze palsy. Pathologic findings of PSP are neuronal loss, gliosis, and neurofibrillary tangles in basal ganglia, diencephalon, and brainstem; there is increasing recognition of clinicopathologic variants of PSP.(1.)
Medical subject headings
- Genetic Predisposition to Disease
- Supranuclear Palsy, Progressive