Host and viral factors affecting clinical performance of a rapid diagnostic test for respiratory syncytial virus in hospitalized children.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 23639327.
- Also identified by DOI 10.1016/j.jpeds.2013.03.067.
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Abstract
Respiratory syncytial virus rapid antigen detection tests (RADT) are used widely. RADT exhibited high specificity (97%) and moderate sensitivity (80%) compared with reverse-transcriptase polymerase chain reaction in 720 hospitalized children <3 years old. Older age, prolonged symptoms, and respiratory syncytial virus genotype-B infection were significantly associated with false-negative results of RADT.
Medical subject headings
- Antigens, Viral
- Chromatography, Affinity
- Respiratory Syncytial Virus Infections
- Respiratory Syncytial Virus, Human