A highly crystalline manganese-doped iron oxide nanocontainer with predesigned void volume and shape for theranostic applications.

Phan, Vu Ngoc; Lim, Eun-Kyung; Kim, Taekhoon; Kim, Minsik; Choi, Yuna; Kim, Byeongyoon; Lee, Myounghoon; Oh, Aram et al. · Adv Mater · 2013

basic_science · Level V

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Abstract

Hollow Mn-doped iron oxide nanocontainers, formed by a novel one-pot synthetic process, fulfill the dual requirements of delivering an effective dose of an anticancer drug to tumor tissue and enabling image-contrast monitoring of the nanocontainer fate through T2 -weighted magnetic resonance imaging, thereby determining the optimal balance between diagnostic and therapeutic moieties in an all-in-one theranostic nanoplatform.

Medical subject headings