Human cortical interneurons take their time.

Marín, Oscar · Cell Stem Cell · 2013

editorial · Level V

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Abstract

In this issue, Maroof et al. (2013) and Nicholas et al. (2013) describe strategies for deriving cortical interneurons from human pluripotent stem cells. Functional maturation of these neurons occurs over a protracted period, which resembles normal human development, and suggests these cells may be useful for modeling brain development and disease.