Same function, different origins: multipotent stromal precursors in lymphoid tissues.
review · Level V
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- Record sourced from PubMed, PMID 23642357.
- Also identified by DOI 10.1016/j.stem.2013.04.011.
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Abstract
The evolutionary and lineage relationships between various stromal cell types that support the immune system are not well understood. Recently, in Immunity, Castagnaro et al. (2013) identified multipotent mesenchymal precursors that specifically give rise to stromal cell types in the spleen, but not other lymphoid tissue, and support injury-induced regeneration.