iOPs: a new tool for studying myelin pathologies?
review · Level V
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- Record sourced from PubMed, PMID 23642358.
- Also identified by DOI 10.1016/j.stem.2013.04.021.
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Abstract
Generating patient-specific oligodendrocyte progenitors capable of repairing myelination defects observed in multiple neurological afflictions holds great therapeutic potential. Recently in Nature Biotechnology, Najm et al. (2013) and Yang et al. (2013) generated these progenitors by direct reprogramming, bringing us closer to their use in disease analysis and autologous transplantation strategies.