Live mammalian cell arrays.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23644546.
- Also identified by DOI 10.1038/nmeth.2473.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
High-content assays have the potential to drastically increase throughput in cell biology and drug discovery, but handling and culturing large libraries of cells such as primary tumor or cancer cell lines requires expensive, dedicated robotic equipment. We developed a simple yet powerful method that uses contact spotting to generate high-density nanowell arrays of live mammalian cells for the culture and interrogation of cell libraries.
Medical subject headings
- High-Throughput Screening Assays
- Tissue Array Analysis