Microfluidic large scale integration of viral-host interaction analysis.
review · Level V
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- Record sourced from PubMed, PMID 23645014.
- Also identified by DOI 10.1039/c3lc00034f.
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Abstract
Viral-host interactions represent potential drug targets for novel antiviral strategies (Flisiak et al., Hepatology, 2008, 47, 817-26). Hence, it is important to establish an adequate platform for identifying and analyzing such interactions. In this review, we discuss bottlenecks in conventional protein-protein interaction methodologies and present the contribution of innovative microfluidic-based technologies towards a solution to these problems with respect to viral-host proteomics.
Medical subject headings
- Microfluidic Analytical Techniques
- Proteins
- Viruses