A gut-heart connection in cardiometabolic regulation.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 23652101.
- Also identified by DOI 10.1038/nm.3196 and PMC identifier 4512286.
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Abstract
GLP-1R agonists are novel new drugs for patients with type 2 diabetes mellitus (T2DM). An intriguing connection between these agents such as liraglutide and native GLP-1 from the gut and the release of the blood pressure lowering cardiac hormone atrial natriuretic peptide (ANP) establishes a new gut – heart connection not only for glycemic control in diabetes, but in overall cardiovascular homeostasis.
Medical subject headings
- Atrial Natriuretic Factor
- Blood Pressure
- Gene Expression Regulation
- Guanine Nucleotide Exchange Factors
- Receptors, Glucagon