22q11.2 deletion syndrome with life-threatening adenovirus infection.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 23660376.
- Also identified by DOI 10.1016/j.jpeds.2013.03.070.
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Abstract
Adenovirus causes significant morbidity and mortality in immunocompromised children. We report how an infusion of HLA-matched sibling donor T lymphocytes rapidly eradicated life-threatening, high-level adenoviremia in a child with complete DiGeorge syndrome (22q11.2 deletion) who went on to reconstitute a diverse, donor-derived, postthymic T-cell repertoire.
Medical subject headings
- Adenovirus Infections, Human
- Bone Marrow Transplantation
- DiGeorge Syndrome
- Immunocompromised Host
- T-Lymphocytes