Lymphatics as a new active player in reverse cholesterol transport.

Kahn, Mark L; Rader, Daniel J · Cell Metab · 2013

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Abstract

Reverse cholesterol transport (RCT), a key function of high-density lipoproteins (HDL), prevents excess cholesterol in tissues. A study in this issue (Lim et al., 2013) suggests that lymphatic vessels are critical for normal RCT and mediate the active trans-endothelial transport of HDL via the HDL receptor SR-BI.