Beyond DNA: programming and inheritance of parental methylomes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23663772.
- Also identified by DOI 10.1016/j.cell.2013.04.044 and PMC identifier 4338575.
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Abstract
Epigenetic reprogramming of parental genomes following fertilization is important to ensure compatibility for totipotency and development thereafter. New studies by Jiang et al. and Potok et al. now demonstrate how the parental DNA methylomes are reset in zebrafish and reveal striking differences from events in mammals.