Microbiota keep the intestinal clock ticking.

Henao-Mejia, Jorge; Strowig, Till; Flavell, Richard A · Cell · 2013

basic_science · Level V

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Abstract

Daily metabolic patterns are regulated in a circadian manner often via the hypothalamic axis. Mukherji et al. now report a surprising role for commensal bacteria in the circadian regulation of glucocorticoid production by intestinal epithelial cells.