Prediction of HIV drug resistance based on virologic, immunologic, clinical, and/or adherence criteria in the Stratall ANRS 12110/ESTHER trial in Cameroon.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 23667264.
- Also identified by DOI 10.1093/cid/cit323.
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Abstract
Our study in Cameroonian rural district hospitals showed that the immunologic and clinical failure criteria had poor performance to identify human immunodeficiency virus drug resistance in a timely manner. Switching to second-line antiretroviral therapy after 2 consecutive viral loads ≥5000 copies/mL, as recommended by the World Health Organization, appeared to be the most appropriate strategy.
Medical subject headings
- Anti-HIV Agents
- Decision Support Techniques
- Drug Resistance, Viral
- HIV Infections
- Viral Load
- Drug Monitoring