Cord blood endothelial colony-forming cells from newborns with congenital diaphragmatic hernia.

Baker, Christopher D; Black, Claudine P; Ryan, Sharon L; Balasubramaniam, Vivek; Abman, Steven H · J Pediatr · 2013

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Abstract

Endothelial colony-forming cells (ECFCs) are decreased in the cord blood of preterm infants with moderate-to-severe bronchopulmonary dysplasia. We quantified ECFCs from infants with congenital diaphragmatic hernia, a neonatal disorder with severe lung hypoplasia. Unlike newborns who develop bronchopulmonary dysplasia, those with congenital diaphragmatic hernia had increased and highly-proliferative cord blood ECFCs.

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