In silico evolution of guiding track designs for molecular shuttles powered by kinesin motors.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23685838.
- Also identified by DOI 10.1039/c3lc41103f.
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Abstract
Molecular shuttles powered by kinesin motors require guiding tracks to perform specific tasks in nanoscale devices. Here, using our simulation of molecular shuttle movements, we describe an in silico evolutionary design method that makes it possible to automatically design the guiding tracks in accordance with their functions defined by designers. With this design method, we designed two types of pre-existing guiding track modules with improved performances, as well as one with a novel function.
Medical subject headings
- Directed Molecular Evolution
- Kinesins
- Microfluidic Analytical Techniques
- Models, Theoretical
- Nanotechnology