Influence of micro- and nano-hydroxyapatite coatings on the osteointegration of metallic (Ti6Al4 V) and bioabsorbable interference screws: an in vivo study.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23689912.
- Also identified by DOI 10.1007/s00590-013-1236-8.
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Abstract
The purpose of this study is to show and compare the fixation and osteointegration capability of metallic and bioabsorbable interference screws. For this, 8×20-mm interference screws were implanted into the bone tunnel in the proximal tibial metaphysis of sheep. The nano- (25 nm±0.8) and microscale (25 μm±0.5) hydroxyapatite were both dip-coated on Ti6Al4 V interference screws via an in vivo study. After the initial 12 weeks of postoperative, the pullout test, histopathology, X-ray diffraction and scanning electron microscopy examinations were performed. This multidisiplined work showed that the coated screws particularly those with nano-sized-HA coating and the bioabsorbable screws enhanced fixation and provided better stabilization, bone ingrowth and osteointegration than that of uncoated and microscale HA-coated screws. The bioabsorbable screws showed better histopathologic results.
Medical subject headings
- Biocompatible Materials
- Bone Screws
- Durapatite
- Osseointegration
- Tibia
- Titanium
Anatomy
- tibia