TiPs: a database of therapeutic targets in pathogens and associated tools.
Where this comes from
- Record sourced from PubMed, PMID 23698860.
- Also identified by DOI 10.1093/bioinformatics/btt289 and PMC identifier 3702258.
- Licence recorded as CC BY-NC.
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Abstract
The need for new drugs and new targets is particularly compelling in an era that is witnessing an alarming increase of drug resistance in human pathogens. The identification of new targets of known drugs is a promising approach, which has proven successful in several cases. Here, we describe a database that includes information on 5153 putative drug-target pairs for 150 human pathogens derived from available drug-target crystallographic complexes. The TiPs database is freely available at http://biocomputing.it/tips. anna.tramontano@uniroma1.it or allegra.via@uniroma1.it.
Medical subject headings
- Databases, Pharmaceutical
- Drug Discovery