Enhanced intestinal glucose and alanine transport in cystic fibrosis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 2370017.
- Also identified by PMC identifier 1378543.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The rise in short-circuit current associated with the active transport of glucose and alanine was measured in intestinal biopsy samples from children with cystic fibrosis. The glucose-induced increase in the short-circuit current was greater in the cystic fibrosis tissues than in control samples over the whole range of concentrations tested (2.5-35 mM), a reflection of an increased maximum rate of transport. Similar results were obtained with alanine. These findings suggest that active Na(+)-linked nutrient transport is enhanced in cystic fibrosis.
Medical subject headings
- Alanine
- Cystic Fibrosis
- Glucose
- Jejunum