Imaging spectrum of CNS coccidioidomycosis: prevalence and significance of concurrent brain and spinal disease.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 23701073.
- Also identified by DOI 10.2214/AJR.12.9264.
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Abstract
The purpose of this study was to evaluate the prevalence and significance of concurrent coccidioidal brain and intraspinal disease. We conducted a retrospective imaging review of 23 patients with proven coccidioidal CNS meningitis. All patients had intracranial abnormalities, and 86% (19/22) who underwent spinal imaging had signs of intraspinal disease, including leptomeningeal enhancement (84%), arachnoiditis (63%), and cord signal abnormalities (37%); seven of 15 patients (47%) who underwent myelography had complete spinal blocks. The high prevalence of concurrent brain and intraspinal coccidioidomycosis supports a low threshold for spinal imaging.
Medical subject headings
- Brain Diseases
- Coccidioidomycosis
- Magnetic Resonance Imaging
- Spinal Diseases
- Tomography, X-Ray Computed