Platelets as cellular effectors of inflammation in vascular diseases.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 23704217.
- Also identified by DOI 10.1161/CIRCRESAHA.113.300512 and PMC identifier 3738064.
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Abstract
Platelets are chief effector cells in hemostasis. In addition, they are multifaceted inflammatory cells with functions that span the continuum from innate immune responses to adaptive immunity. Activated platelets have key thromboinflammatory activities in a variety of vascular disorders and vasculopathies. Recently identified inflammatory and immune activities provide insights into the biology of these versatile blood cells that are directly relevant to human vascular diseases.
Medical subject headings
- Blood Platelets
- Platelet Activation
- Thrombosis
- Vascular Diseases
- Vasculitis