New balance in pluripotency: reprogramming with lineage specifiers.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 23706730.
- Also identified by DOI 10.1016/j.cell.2013.04.051.
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Abstract
Induction of pluripotency in somatic cells has been achieved by myriad combinations of transcription factors that belong to the core pluripotency circuitry. In this issue, Shu et al. report reprogramming with lineage specifiers, lending support to the view of the pluripotent state as a fine balance between competing differentiation forces.
Medical subject headings
- Induced Pluripotent Stem Cells
- Transcription Factors