Mutation analysis of papillary tubal hyperplasia associated with ovarian atypical proliferative serous tumor and low-grade serous carcinoma.
Level V
Where this comes from
- Record sourced from PubMed, PMID 23711666.
- Also identified by DOI 10.1016/j.ajog.2013.05.044.
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Abstract
We present a patient with ovarian atypical proliferative serous tumor and low-grade serous carcinoma, related to KRAS mutation. Bilateral fallopian tubes had papillary tubal hyperplasia, providing additional evidence that it is the putative precursor of low-grade serous tumors. Mutation analysis of papillary tubal hyperplasia has not been done in previous literature.
Medical subject headings
- Cystadenocarcinoma, Serous
- Fallopian Tube Neoplasms
- Fallopian Tubes
- Mutation
- Ovarian Neoplasms
- Precancerous Conditions
- Proto-Oncogene Proteins
- ras Proteins