Engineering polymeric microparticles as theranostic carriers for selective delivery and cancer therapy.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23712912.
- Also identified by DOI 10.1002/adhm.201300077.
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Abstract
Multifunctional polymeric nano- and microparticles are engineered as theranostic carriers and their selective size-dependent cellular uptake is demonstrated. It is found that effective uptake and accumulation of nanoparticles occurs in both normal and cancer cells, whereas, that of microparticles occurs in cancer cells but not in normal cells, allowing cancer cells to be specifically targeted for local drug delivery.
Medical subject headings
- Antineoplastic Agents
- Drug Carriers
- Lactic Acid
- Polyglycolic Acid
- Quantum Dots