Transoral robotic approach to carcinoma of unknown primary.
prospective_cohort · Level II
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- Record sourced from PubMed, PMID 23720223.
- Also identified by DOI 10.1002/hed.23385 and PMC identifier 4266274.
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Abstract
The management of carcinoma of unknown primary (CUP) is one of the challenging conditions in head and neck oncologic surgery. Despite various diagnostic tools, the primary tumor site in more than half of cases remains unidentified. The purpose of this study was to assess the feasibility and efficiency of utilizing transoral robotic surgery (TORS) for the diagnosis and treatment of CUP in the head and neck. In this prospective, single-institutional, clinical TORS trial, 22 of 181 patients were treated for CUP between 2008 and 2012. Among all those 22 patients, primary tumor site identification and complete tumor removal was achieved in 17 patients (77.3%) with TORS. Tonsil (59.1%) and base of tongue (18.1%) were identified as the most common tumor locations. Together with panendoscopy, directed biopsies, and positron emission tomography (PET)/CT, TORS is a valuable option in the identification and treatment of primary tumor sites.
Medical subject headings
- Carcinoma, Squamous Cell
- Natural Orifice Endoscopic Surgery
- Neoplasms, Unknown Primary
- Robotic Surgical Procedures
- Tongue Neoplasms
- Tonsillar Neoplasms