Orthogonal adsorption onto nano-graphene oxide using different intermolecular forces for multiplexed delivery.

Wang, Feng; Liu, Biwu; Ip, Alexander C-F; Liu, Juewen · Adv Mater · 2013

basic_science · Level V

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Abstract

Nano-graphene oxide can adsorb both doxorubicin and zwitterionic dioleoyl-sn-glycero-3-phosphocholine (DOPC) liposomes in an orthogonal and non-competing manner with high capacities based on different surface and intermolecular forces taking place on the heterogeneous surface of the graphene oxide. The system forms stable colloids, allowing co-delivery of both cargos to cancer cells.

Medical subject headings