Central nervous system herpes simplex and varicella zoster virus infections in natalizumab-treated patients.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 23728144.
- Also identified by DOI 10.1093/cid/cit376.
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Abstract
We report on 20 natalizumab-treated patients with multiple sclerosis who developed laboratory-confirmed central nervous system (CNS) herpesvirus infections. In addition to progressive multifocal leukoencephalopathy, other CNS opportunistic infections have been rarely reported during natalizumab treatment. We encourage heightened awareness due to the risk for serious outcomes.
Medical subject headings
- Antibodies, Monoclonal, Humanized
- Encephalitis, Herpes Simplex
- Encephalitis, Varicella Zoster
- Meningitis, Viral