Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23743667.
- Also identified by DOI 10.1039/c3lc41343h and PMC identifier 3740541.
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Abstract
We fabricated a microfluidic device consisting of ciliated micropillars, forming a porous silicon nanowire-on-micropillar structure. We demonstrated that the prototype device can preferentially trap exosome-like lipid vesicles, while simultaneously filtering out proteins and cell debris. Trapped lipid vesicles can be recovered intact by dissolving the porous nanowires in PBS buffer.
Medical subject headings
- Lipids
- Microfluidic Analytical Techniques