Novel regulator of enterohepatic bile acid signaling protects against hypercholesterolemia.
Where this comes from
- Record sourced from PubMed, PMID 23747242.
- Also identified by DOI 10.1016/j.cmet.2013.05.005 and PMC identifier 3805117.
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Abstract
Hypercholesterolemia is a major cause of cardiovascular disease and can be treated by targeting bile acid and cholesterol metabolism. Vergnes et al. (2013) now identify Diet1 as a novel regulator of fibroblast growth factor 15/19 production and bile acid biosynthesis.
Medical subject headings
- Bile Acids and Salts
- Carrier Proteins
- Cholesterol 7-alpha-Hydroxylase
- Fibroblast Growth Factors
- Lipid Metabolism