NOA: a cytoscape plugin for network ontology analysis.

Zhang, Chao; Wang, Jiguang; Hanspers, Kristina; Xu, Dong; Chen, Luonan; Pico, Alexander R · Bioinformatics · 2013

basic_science · Level V

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Abstract

The Network Ontology Analysis (NOA) plugin for Cytoscape implements the NOA algorithm for network-based enrichment analysis, which extends Gene Ontology annotations to network links, or edges. The plugin facilitates the annotation and analysis of one or more networks in Cytoscape according to user-defined parameters. In addition to tables, the NOA plugin also presents results in the form of heatmaps and overview networks in Cytoscape, which can be exported for publication figures. The NOA plugin is an open source, Java program for Cytoscape version 2.8 available via the Cytoscape App Store (http://apps.cytoscape.org/apps/noa) and plugin manager. A detailed user manual is available at http://nrnb.org/tools/noa. .ucsf.edu

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