DMEAS: DNA methylation entropy analysis software.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23749987.
- Also identified by DOI 10.1093/bioinformatics/btt332 and PMC identifier 3722522.
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Abstract
DMEAS is the first user-friendly tool dedicated to analyze the distribution of DNA methylation patterns for the quantification of epigenetic heterogeneity. It supports the analysis of both locus-specific and genome-wide bisulfite sequencing data. DMEAS progressively scans the mapping results of bisulfite sequencing reads to extract DNA methylation patterns for contiguous CpG dinucleotides. It determines the DNA methylation level and calculates methylation entropy for genomic segments to enable the quantitative assessment of DNA methylation variations observed in cell populations. DMEAS program, user guide and all the testing data are freely available from http://sourceforge.net/projects/dmeas/files/
Medical subject headings
- DNA Methylation
- Sequence Analysis, DNA
- Software