Perineural spread of cervical cancer to the sciatic nerve.

Howe, Benjamin Matthew; Amrami, Kimberly K; Nathan, Mark A; Garcia, Joaquin J; Spinner, Robert J · Skeletal Radiol · 2013

case_report · Level V

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Abstract

In this report we present a patient with a recent diagnosis of cervical adenocarcinoma with progressive left lower extremity pain and weakness. MR imaging of the pelvis and subsequent FDG CT/PET were complementary in demonstrating abnormalities worrisome for perineural spread of malignancy, which was confirmed with an open fascicular biopsy of the sciatic nerve. We review the imaging and propose a mechanism of perineural spread to the sciatic nerve, which we believe is supported by the imaging in this case.

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