Hydrocephalus induced by cyclophosphamide in chick embryos.

Singh, S N; Mohanty, S; Singh, G · Neurosurgery · 1990

basic_science · Level V

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Abstract

Cyclophosphamide was injected into the yolk sac of chick embryos for 6 days (Days 0-5). Embryos collected on the 21st day of incubation had a 37% incidence of hydrocephalus. Agenesis or stenosis of the aqueduct, as well as hypertrophy of the choroid plexus, was observed in 20% of the embryos.

Medical subject headings