Inside-out connections: the ER meets the plasma membrane.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23791170.
- Also identified by DOI 10.1016/j.cell.2013.05.054 and PMC identifier 6783275.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Junctions that connect the endoplasmic reticulum (ER) and the plasma membrane (PM) are unique yet ubiquitous subcellular compartments. Giordano et al. now report that extended synaptotagmins (E-Syts) promote their formation, providing fundamental insight into the molecular machinery controlling ER and plasma membrane crosstalk.
Medical subject headings
- Calcium
- Cell Membrane
- Endoplasmic Reticulum
- Phosphatidylinositol 4,5-Diphosphate
- Synaptotagmins