Guarding against collateral damage during chromatin transactions.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 23791174.
- Also identified by DOI 10.1016/j.cell.2013.05.044.
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Abstract
Signal amplifications are vital for chromatin function, yet they also bear the risk of transforming into unrestrained, self-escalating, and potentially harmful responses. Examples of inbuilt limitations are emerging, revealing how chromatin transactions are confined within physiological boundaries.
Medical subject headings
- Chromatin
- DNA Repair
- Transcription, Genetic