Cellular fatty acid metabolism and cancer.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 23791484.
- Also identified by DOI 10.1016/j.cmet.2013.05.017 and PMC identifier 3742569.
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Abstract
Cancer cells often have characteristic changes in metabolism. Cellular proliferation, a common feature of all cancers, requires fatty acids for synthesis of membranes and signaling molecules. Here, we provide a view of cancer cell metabolism from a lipid perspective, and we summarize evidence that limiting fatty acid availability can control cancer cell proliferation.
Medical subject headings
- Fatty Acids
- Lipid Metabolism
- Neoplasms