Cake: a bioinformatics pipeline for the integrated analysis of somatic variants in cancer genomes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23803469.
- Also identified by DOI 10.1093/bioinformatics/btt371 and PMC identifier 3740632.
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Abstract
We have developed Cake, a bioinformatics software pipeline that integrates four publicly available somatic variant-calling algorithms to identify single nucleotide variants with higher sensitivity and accuracy than any one algorithm alone. Cake can be run on a high-performance computer cluster or used as a stand-alone application. Availabilty: Cake is open-source and is available from http://cakesomatic.sourceforge.net/
Medical subject headings
- Genetic Variation
- Neoplasms
- Software