Piecing together the extracellular puzzle.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23827672.
- Also identified by DOI 10.1016/j.cell.2013.06.014.
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Abstract
Large-scale screens to identify protein interactions typically underperform with eukaryotic extracellular proteins. In this issue, Özkan et al. report development of a high-throughput assay designed specifically for extracellular proteins that uncovers a wealth of new interactions among three protein superfamilies in Drosophila and sets the stage for more extensive screens.
Medical subject headings
- Drosophila Proteins
- Drosophila melanogaster
- Fibronectins
- Immunoglobulins
- Protein Interaction Maps
- Proteins