lincRNAs: genomics, evolution, and mechanisms.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 23827673.
- Also identified by DOI 10.1016/j.cell.2013.06.020 and PMC identifier 3924787.
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Abstract
Long intervening noncoding RNAs (lincRNAs) are transcribed from thousands of loci in mammalian genomes and might play widespread roles in gene regulation and other cellular processes. This Review outlines the emerging understanding of lincRNAs in vertebrate animals, with emphases on how they are being identified and current conclusions and questions regarding their genomics, evolution and mechanisms of action.
Medical subject headings
- Biological Evolution
- Gene Expression Regulation
- RNA, Long Noncoding