CHD7 in charge of neurogenesis.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 23827700.
- Also identified by DOI 10.1016/j.stem.2013.06.010.
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Abstract
In this issue of Cell Stem Cell, Feng et al. (2013) report that the gene mutated in human CHARGE syndrome, ATP-dependent chromatin remodeling factor CHD7, contributes to the control of neurogenesis. The authors also report that exercise ameliorates these defects and suggest it as an intervention worthy of study in CHARGE syndrome.
Medical subject headings
- DNA-Binding Proteins
- Gene Expression Regulation, Developmental
- Neural Stem Cells
- Neurogenesis
- SOXC Transcription Factors