The identification of nitric oxide as endothelium-derived relaxing factor.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 23833290.
- Also identified by DOI 10.1161/CIRCRESAHA.113.301577 and PMC identifier 3711180.
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Abstract
The identification of endothelium-derived relaxing factor as nitric oxide (NO) dramatically altered the course of vascular biology, as well as other biomedical disciplines. The ubiquity of this natural product of cell metabolism and the complexity of its biochemistry provide a rich source of molecular mediators of phenotype in health and disease.
Medical subject headings
- Endothelium-Dependent Relaxing Factors
- Nitric Oxide
- Vasodilation