Special article: the endothelial glycocalyx: emerging concepts in pulmonary edema and acute lung injury.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 23835455.
- Also identified by DOI 10.1213/ANE.0b013e3182975b85 and PMC identifier 3790575.
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Abstract
The endothelial glycocalyx is a dynamic layer of macromolecules at the luminal surface of vascular endothelium that is involved in fluid homeostasis and regulation. Its role in vascular permeability and edema formation is emerging but is still not well understood. In this special article, we highlight key concepts of endothelial dysfunction with regards to the glycocalyx and provide new insights into the glycocalyx as a mediator of processes central to the development of pulmonary edema and lung injury.
Medical subject headings
- Acute Lung Injury
- Endothelium
- Glycocalyx
- Pulmonary Edema