A triggered DNA hydrogel cover to envelop and release single cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23836697.
- Also identified by DOI 10.1002/adma.201301175.
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Abstract
We develop an enzyme-triggered permeable DNA hydrogel cover to envelop and release single cells in microwells. The porous structure of the DNA hydrogel allows nutrients and waste to pass through, leading to a cell viability as high as 98%. The design provides a general method to culture, monitor, and manipulate single cells, and has potential applications in cell patterning and studying cell communication.
Medical subject headings
- DNA
- Hydrogel, Polyethylene Glycol Dimethacrylate