Higher incidence of acute kidney injury with intravenous colistimethate sodium compared with polymyxin B in critically ill patients at a tertiary care medical center.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 23840000.
- Also identified by DOI 10.1093/cid/cit453.
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Abstract
Nephrotoxicity was assessed in 173 critically ill patients receiving intravenous colistin or polymyxin B; it occurred in 60.4% and 41.8%, respectively. Further investigation is necessary to elucidate the reason for the difference in nephrotoxicity observed between the groups and to assess the impact of severity of illness and dosing/administration.
Medical subject headings
- Acute Kidney Injury
- Anti-Bacterial Agents
- Colistin
- Polymyxin B