A new diamond biosensor with integrated graphitic microchannels for detecting quantal exocytic events from chromaffin cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23847004.
- Also identified by DOI 10.1002/adma.201300710.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
An MeV ion-microbeam lithographic technique can be successfully employed for the fabrication of an all-carbon miniaturized cellular biosensor based on graphitic microchannels embedded in a single-crystal diamond matrix. The device is functionally characterized for the in vitro recording of quantal exocytic events from single chromaffin cells, with high sensitivity and signal-to-noise ratio, opening promising perspectives for the realization of monolithic all-carbon cellular biosensors.
Medical subject headings
- Biosensing Techniques
- Chromaffin Cells
- Diamond
- Exocytosis