Spinal manifestation of hydatid disease: a case series of 36 patients.

Abstract

Vertebral hydatid cysts are found in <1% of all cases of hydatidosis. The pathology has an infiltrative malignant nature, affecting the vertebral body with possible extension in the epidural space. This pathomechnism is associated with a high rate of morbidity, mortality, and relapse. Decompressive surgery combined with antihelminthic therapy is recommended to eradicate the disease and prevent recurrence. Between 1990 and 2007, 36 patients with a mean age of 31 years were diagnosed as having spinal hydatid disease and underwent surgery on several occasions for multiple recurrences. Combined chemotherapy with albendazole also was given. Initial surgery and chemotherapy steadied clinical progression and functional deterioration, but with a recurrence rate of 89% and an average time to disease recurrence of 2.5 years, did not improve the known malignant course of disease in comparison to the literature. The devastating and malignant course of this disease, which affects mostly young patients, demands continuous development of preventive care in endemic regions, the early detection and screening of the diseased patients, and eventually the advancement of the combined medical and surgical treatment.