Vector decoys trick the immune response.
Where this comes from
- Record sourced from PubMed, PMID 23863831.
- Also identified by DOI 10.1126/scitranslmed.3006633.
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Abstract
Humoral immunity to adeno-associated viral vectors can be overcome by using empty capsid mutant "decoys" for preexisting antibodies (Mingozzi et al., this issue).
Medical subject headings
- Genetic Therapy
- Genetic Vectors
- Immunity, Humoral