Genetically engineered peptides for inorganics: study of an unconstrained bacterial display technology and bulk aluminum alloy.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23868808.
- Also identified by DOI 10.1002/adma.201301646 and PMC identifier 3793233.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The first-ever peptide biomaterial discovery using an unconstrained engineered bacterial display technology is reported. Using this approach, we have developed genetically engineered peptide binders for a bulk aluminum alloy and use molecular dynamics simulation of peptide conformational fluctuations to demonstrate sequence-dependent, structure-function relationships for metal and metal oxide interactions.
Medical subject headings
- Alloys
- Aluminum
- Escherichia coli
- Genetic Engineering
- Peptide Library
- Peptides